12/8/2023 0 Comments Serum definitionIn this regard, the aim of the current study was measurement and analysis of serum levels of leptin and resistin in patients with knee OA with different body mass index (BMI). It has been suggested that their systemic effects link obesity and OA. There has been increasing interest in the role of adipokines in the pathogenesis of OA in the recent years. Apart from the mechanical effect of obesity via increase in mechanical overload of weight-bearing joints, an association with hand OA has been observed. Obesity is considered a major risk factor for the development and progression of knee osteoarthritis (OA).
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